Zachary Quinto to make Broadway bow in 'Menagerie'

FILE - This April 14, 2013 file photo shows actor Zachary Quinto at the MTV Movie Awards in Sony Pictures Studio Lot in Culver City, Calif. Producers Jeffrey Richards said Thursday Quinto will star in the American Repertory Theater's production of ?The Glass Menagerie? for a 17-week engagement starting this September. Quinto, who plays Spock in the ?Star Trek? reboots and wowed audiences in a recent off-Broadway production of ?Angels In America,? will be making his Broadway debut as Tom. (Photo by Jordan Strauss/Invision/AP)

FILE - This April 14, 2013 file photo shows actor Zachary Quinto at the MTV Movie Awards in Sony Pictures Studio Lot in Culver City, Calif. Producers Jeffrey Richards said Thursday Quinto will star in the American Repertory Theater's production of ?The Glass Menagerie? for a 17-week engagement starting this September. Quinto, who plays Spock in the ?Star Trek? reboots and wowed audiences in a recent off-Broadway production of ?Angels In America,? will be making his Broadway debut as Tom. (Photo by Jordan Strauss/Invision/AP)

NEW YORK (AP) ? Another Tennessee Williams masterpiece is coming to Broadway and it's bringing Zachary Quinto and Cherry Jones along for the ride.

Producers Jeffrey Richards said Thursday he'll transfer the American Repertory Theater's production of "The Glass Menagerie" to New York for a 17-week engagement starting this September.

Quinto, who plays Spock in the "Star Trek" reboots and wowed audiences in a recent off-Broadway production of "Angels In America," will be making his Broadway debut as Tom.

Jones, the two-time Tony Award winner for "Doubt" and "The Heiress" who played President Allison Taylor in the TV series "24," will play Amanda Wingfield.

They'll be joined by Celia Keenan-Bolger, fresh off her role as Wendy in Broadway's "Peter and the Starcatcher," and Brian J. Smith, recently in "The Columnist." John Tiffany, who helmed "Once," will direct.

Performances begin Sept, 5 with an opening night set for Sept. 26. The venue will be a Shubert Theatre that has yet to be announced. The show originated at the acclaimed American Repertory Theater outside Boston this winter.

The play centers on an aging Southern belle who hopes her son can fulfill her dreams of finding the perfect "gentleman caller" for her shy and damaged daughter.

The last time "The Glass Menagerie" hit Broadway was 2005 starring Jessica Lange and Christian Slater. The latest revival comes on the heels of "A Streetcar Named Desire" last year with Blair Underwood and Nicole Ari Parker, and "Cat on a Hot Tin Roof" this year with Scarlett Johansson.

___

Online: http://www.TheGlassMenagerieBroadway.com

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-04-25-US-Theater-The-Glass-Menagerie/id-3f3b3617632a419b80e9e710acb501a1

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Cancer rate 15% higher than normal for 9/11 first responders | PIX 11

A new study finds the cancer rate among 9/11 responders is higher than normal.

Researchers say it?s 15% higher than among people who were not exposed to the ground zero toxins.

The study was done by Mount Sinai Hospital?s World Trade Center Health Program.

It found an increase primarily in three types of the disease: ?thyroid, prostate and blood cancers, such as leukemia and lymphoma.

Source: http://pix11.com/2013/04/23/cancer-rate-15-higher-than-normal-for-911-first-responders/

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S.Africa's rand slips on disappointing Chinese factory data

JOHANNESBURG (Reuters) - South Africa's rand remained on a weaker footing against the dollar on Monday, weighed down by fears over disruptions to the national electricity supply and by weaker-than-expected Chinese manufacturing data.

The rand was at 9.2800 to the dollar at 0630 GMT, down 0.6 percent from Monday's close in New York.

It weakened yesterday after South African power utility Eskom said it was prepared to introduce rolling blackouts this winter in some parts of the grid to prevent a complete system collapse, which would inflict far greater damage on the economy.

The rand was also pushed lower after data showed growth in the factory sector of the world's second-largest economy dipped in April as new export orders shrank.

"The rand moved this morning based primarily on the weaker Chinese data," said Absa Capital trader Duncan Howes. "Given that China is South Africa's largest trading partner it can have a fairly substantial effect on our trade."

Howes said domestic factors would keep the rand under pressure in the short term and that it was likely to trade in the 9.22-9.34 range.

Government bonds firmed, with the yield on the 2015 paper declining 6 basis points to 5.29 percent and that on the 2026 instrument falling 1.5 basis points to 6.885 percent.

South Africa's Treasury will auction 2.35 billion rand of its 2023, 2036 and 2041 government bonds later on Tuesday.

Source: http://news.yahoo.com/africas-rand-slips-disappointing-chinese-factory-data-070006695--finance.html

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Hagel to meet Egypt's leaders, push military ties

CAIRO (AP) ? By including Cairo on his first Mideast tour as defense secretary, Chuck Hagel is highlighting the Obama administration's hope of preserving influence with the Egyptian military as the country struggles with its transition to democracy.

After stops in Israel, Jordan and Saudi Arabia, Hagel flew to the Egyptian capital for his first face-to-face meetings with Egypt's top leaders. In their talks Wednesday, he planned to stress the value of close military ties with a country that is deeply divided in the wake of the 2011 revolution that ousted longtime President Hosni Mubarak.

Egypt was the first Arab country to sign a peace treaty with Israel. The U.S. is deeply concerned, however, that continued instability in Egypt will have broader consequences in a region already rocked by unrest, including in the increasingly lawless Sinai Peninsula.

U.S. Secretary of State John Kerry visited Egypt in March and rewarded it for President Mohammed Morsi's pledges of political and economic reform by releasing $250 million in American aid.

Morsi came to power in June 2012 as Egypt's first freely elected president.

Hagel was scheduled to meet with Morsi as well as Defense Minister Abdel Fattah al-Sisi.

On Tuesday the legal adviser to Morsi resigned, alleging that the Muslim Brotherhood has monopolized decision-making and encroached on the governing of the country.

The resignation letter by Mohammed Fouad Gadallah brought the harshest criticism yet from inside the presidency. Opponents of Morsi long have accused the Brotherhood of being the real power behind the president and say the group's attempts to dominate power have fueled the country's turmoil.

Morsi, who hails from the Brotherhood, denied in a TV interview earlier this week that the group intervenes in decision-making.

Hagel flew to Cairo from Riyadh, where he met Tuesday evening with top officials, including Crown Prince Salman bin Abdulaziz al-Saud, who serves as the kingdom's defense minister as well. Hagel also held talks Tuesday in Jordan and Israel.

Source: http://news.yahoo.com/hagel-meet-egypts-leaders-push-military-ties-061042664--politics.html

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Michael Jackson wrongful death trial set to get underway Monday

LOS ANGELES (Reuters) - The civil trial over the death of Michael Jackson is set to get formally underway next week after jury selection was completed on Tuesday in the $40 billion case that pits the pop star's mother against concert promoters AEG Live.

Six alternate jurors were chosen on Tuesday following the selection a day earlier of a jury of six men and six women for what is expected to be an emotional three-month trial.

The conclusion of the month-long search for a jury set the stage for opening statements to begin in Los Angeles Superior Court on Monday.

Jackson's 82-year-old mother, Katherine, is suing AEG Live, the promoters of his never-realized series of 2009 London comeback concerts, for the wrongful death of her son.

The lawsuit alleges AEG Live was negligent in hiring Dr. Conrad Murray to care for the singer while he rehearsed for a series of 50 shows.

AEG Live contends that it did not hire or supervise Murray and that Jackson was addicted to prescription drugs for years before he agreed to do the "This Is It" London concerts.

The concert promoters also argue that they could not have foreseen that Murray, who was convicted in 2011 of involuntary manslaughter in Jackson's death, posed a danger to the singer.

Jackson, 50, died in Los Angeles on June 25, 2009, from a lethal dose of the surgical anesthetic propofol that Murray was administering for sleep problems. Murray, who is not being sued, formally appealed against his criminal conviction on Monday.

Potential witnesses in the civil trial include Jackson's mother, his two oldest children, Prince, 16, and Paris, 15, as well as Murray, singers Prince and Diana Ross, and Jackson's ex-wives, Lisa Marie Presley and Debbie Rowe.

Katherine Jackson and her son's three children are seeking some $40 billion in damages from privately held AEG Live for loss of the singer's earnings and other damages. The final amount will be determined by the jury should it hold AEG Live negligent.

(Reporting by Jill Serjeant; Editing by Eric Beech)

Source: http://news.yahoo.com/michael-jackson-wrongful-death-trial-set-underway-monday-011959836.html

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Gambling company 888 sees U.S. online poker boost from 2015

By Keith Weir

LONDON (Reuters) - Gambling company 888 Holdings Plc expects to launch online poker in Nevada this summer and should start to see the full effects of more open U.S. markets from 2015.

Nevada, home to gambling center Las Vegas, granted the London-listed company a license last month and 888 is also seeking clearance to operate in New Jersey, another state where a ban on Internet betting is being lifted.

"In Nevada we are awaiting final sign-off by the gaming control board on our software," 888 CEO Brian Mattingley told Reuters on Tuesday, adding that its online poker product should be live by the third quarter.

Mattingley was optimistic that New Jersey, another center for land-based American gambling, might clear the way for both online casino and poker games when detailed legislation is finalized, rather than limiting it to poker as is the case in Nevada.

Internet betting was banned by Congress in 2006, dealing a blow to companies like 888 which had set up in the United States. However, tax-hungry states are now relaxing rules, creating opportunities for European players with years of expertise in the sector.

"I imagine we will start to see some really influential numbers to our business from 2015," said Mattingley, adding that next year would involve a lot of marketing spending as companies jostle for position in the United States.

A strong performance in Spain and Italy fuelled a nine percent rise in revenues to $103 million in the first three months of the year, 888 said.

Business in Italy had been boosted after the government allowed companies to offer online slot machine products which are popular with gamblers playing Internet casino games.

Mattingley said he hoped Spain would follow suit by lifting a ban on slots - effectively the online version of "one-arm bandit" arcade games.

"Once you prohibit something, you open the door to illegal trading. The Italians saw a huge amount of tax revenue disappearing," he said.

The company planned to offer online sports betting in both Italy and Spain by the summer, Mattingley added.

888 shares rose 0.7 percent to 167.7 pence by 0415 EDT (0815 GMT).

The prospects for a return to the United States helped drive a doubling in 888's share price since the middle of 2012 and the company is now worth almost 600 million pounds ($915 million). ($1 = 0.6560 British pounds)

(Writing by Keith Weir; Editing by Helen Massy-Beresford)

Source: http://news.yahoo.com/gambling-company-888-sees-u-online-poker-boost-090804147--finance.html

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Catholic Church withdraws subpoena to Obama on birth control

WASHINGTON (Reuters) - Scaling down a legal fight with the White House, the Roman Catholic Archdiocese of New York has agreed to drop a request for documents about the government's requirement of insurance coverage for birth control, a court filing on Monday said.

The archdiocese sent a subpoena to President Barack Obama's administration in February asking for documents from White House staff, including Obama himself, for use in a church lawsuit against the contraception mandate.

Citing the burden involved and calling a subpoena of the president's office inappropriate, the White House asked a federal judge to toss out the subpoena on April 4.

A notice filed in U.S. District Court in Washington late on Monday said the archdiocese agreed to withdraw its subpoena. It did not say why.

A lawyer for the archdiocese declined to comment on Tuesday. A spokeswoman for the U.S. Justice Department, which represented the White House in court, had no immediate comment.

The archdiocese is continuing its lawsuit in Brooklyn federal court challenging the Obama administration's health policy requirement that employers generally include coverage of birth control in health insurance plans they offer workers.

The Catholic Church teaches that artificial birth control is sinful because it violates natural law.

Part of the 2010 healthcare law championed by Obama and congressional Democrats, the birth control mandate has some exceptions for religious employers but the New York archdiocese said it expected to incur nearly $200 million each year in penalties if it refuses to comply.

(Reporting by David Ingram; editing by Andrew Hay)

Source: http://news.yahoo.com/catholic-church-withdraws-subpoena-obama-birth-control-184739148.html

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Apple Wins Motorola ITC Patent Suit - The Next Web

The US International Trade Commission has sided with Apple (PDF) in a patent lawsuit brought by Google and Motorola Mobility that challenged a proximity sensor feature on the iPhone 4, Bloomberg reports.

The commission issued a finding of no violation on Monday and terminated the investigation.

Motorola originally filed the complaint in 2010. A judge had found Apple in violation of one of Motorola?s patents in an initial ruling, but the commission overruled the finding and cleared Apple.

The legal dispute between Apple and Motorola has gone on for almost three years, but it hasn?t reached the same level of drama as the Apple vs. Samsung dispute. Google managed to purchase Motorola in the midst of the disagreement, bringing the two companies in head-to-head conflict.

However, Motorola has lost some momentum after facing investigations into its use of standards-committed patents in legal action against Apple.

Update:?Motorola has issued a brief statement on the decision:

?We?re disappointed with this outcome and are evaluating our options.?

Photo credit:?Michael Nagle/Getty Images

Source: http://thenextweb.com/apple/2013/04/23/apple-successfully-defends-against-motorola-itc-patent-case-over-iphone-proximity-sensor/

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Bill Clinton honored at GLADD Awards

Former President Bill Clinton received the first advocate for change award at the annual GLAAD Media Awards, which celebrates inclusive representations of the LGBT community in the media.

By Michael Cidoni Lennox,?AP Entertainment Writer / April 21, 2013

Former US President Bill Clinton speaks on stage after he received the advocate for change award during the 24th Annual GLAAD Media Awards at JW Marriott Los Angeles in L.A.

Jonathan Alcorn/Reuters

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NBC's sitcom "The New Normal," FX's thriller "American Horror Story: Asylum" and NBC's daytime drama "Days of Our Lives" took home top TV honors at the 24th annual GLAAD Media Awards held Saturday night in Los Angeles.

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The GLAAD awards pay tribute to "inclusive representations of the lesbian, gay, bisexual and transgender community and the issues that affect their lives."

The event, hosted by actress-producer-director Drew Barrymore, boasted such Hollywood heavyweights as presenters Jennifer Morrison, Charlize Theron, Betty White and Leonardo DiCaprio.

Other winners included "Perks of Being a Wallflower," which was named outstanding film: wide release. Former President?Bill?Clinton?was given the first advocate for change award.

On the arrivals line, longtime?Clinton?friend, Oscar-winner Mary Steenburgen, defended the former president's controversial honor. Under?Clinton's?administration came the Defense of Marriage Act, which bars federal recognition of same-sex marriage, as well as the "don't ask, don't tell" military policy.

"Actually, ("don't ask, don't tell") was a sorrow for him," Steenburgen said. "So, I think he's spent a large part of his life making up for that. But I tell you this: He's never not had his heart in the right place, in terms of the gay community."

Many who walked the press gauntlet shared personal stories. Actor Justin Bartha said a brother's coming out moved him both personally and professionally.

"It was an inspiring moment ? I'm sure for him and definitely me and my whole family," Bartha noted. "So, it was at the forefront of my mind when looking at (the role of half of a gay couple in "The New Normal")."

"Kyle XY" actor Matt Dallas discussed his decision to come out publicly earlier this year. MSNBC news anchor Thomas Roberts talked about the recent marriage to his male partner of 12 years. Entertainment blogger Perez Hilton detailed the challenges of being the single gay parent of newly adopted child.

And transgendered Chaz Bono expressed hopes for the gay lesbian bisexual transgender community's future.

"I mean, I think the goal always has to be equality in all aspects under the law," he said. "You're never going to eradicate discrimination. We see that with other minorities. Racism is still, unfortunately, alive and well. But equal protection under the law makes a huge difference. So, I think, for me, that is the goal, that is the thing to strive for."

Additional 2013 GLAAD Media Awards were presented in New York on March 16. The final awards will be presented in San Francisco May 11.

On the web:?www.glaad.org

Follow Michael Cidoni Lennox at www.twitter.com/MikeCLennox

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/1uOwj4rXuZY/Bill-Clinton-honored-at-GLADD-Awards

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Iraqis go to polls for first time since US pullout

BAGHDAD (AP) ? Iraq carried out its first election since the U.S. military withdrawal without major bloodshed Saturday in a major test for Iraqi security forces as they face a reviving al-Qaida insurgency. But delayed elections in two provinces wracked by anti-government protests and complaints about missing names on voter rolls overshadowed the vote.

The results will be a key measure of support for the country's vying political coalitions and could boost the victors' chances heading into next year's parliamentary elections. Thousands of candidates from 50 electoral blocs were vying for 378 seats on provincial councils, which hold sway over public works projects and other decisions at the local level.

Officials ratcheted up security to thwart insurgent attempts to disrupt the vote. Nearly all cars were ordered off the roads in major cities, leaving streets eerily empty and giving children a chance to play soccer in the middle of highways.

Scattered violence ? mainly mortar shells and small bombs ? struck near polling places. But they resulted in no fatalities ? a departure from a wave of bloodshed earlier in the week. Six people were reported wounded Saturday.

As in past elections, voters dipped their fingers in purple ink after casting their ballots to prevent repeat voting.

Among them was Oday Mohammed, a businessman who brought his mother, wife and children along with him to vote for a candidate from Prime Minister Nouri al-Maliki's State of Law bloc. He said he believes both candidates and voters are growing more experienced with the democratic process following the 2003 ouster of dictator Saddam Hussein.

"Not all politicians are corrupt. There are some good people," he said at a polling center in the mainly Shiite district of Kazimiyah.

The vote comes at a time of rising tensions between Iraq's Sunni Arab minority and the Shiite majority that has dominated politics since the U.S.-led invasion a decade ago.

In a reflection of those sectarian strains, many voters said they were encouraged to participate by religious leaders.

"I don't have any hope that the situation will improve, but I had to take part because our clerics asked us to so we don't lose out like in in the past," said Anwar al-Obaidi, a 60-year old Sunni barber in Baghdad.

Muqdad al-Shuraifi, a member of the electoral commission, said after polls closed that a preliminary count showed 51 percent of eligible voters cast ballots. That is the same turnout as during the last provincial elections in 2009.

Full election results were not expected for several days.

Many Iraqis are frustrated with the lack of progress despite several earlier regional and national elections, which were protected with help from the U.S. Several said they saw no point in casting ballots.

"All the politicians and provincial officials, whether Sunni or Shiite, are nothing but thieves and liars," said Ali Farhan, a 35-year-old taxi driver in eastern Baghdad, in explaining his choice not to vote.

Militants stepped up attacks ahead of the vote. A wave of car bombings and other attacks Monday killed at least 55 people and wounded more than 200. Another bombing at a packed cafe late Thursday that left 32 dead. And at least 14 candidates were assassinated in recent weeks.

Several would-be voters in Baghdad's mainly Sunni neighborhood of Azamiyah could not find their names on voting rolls at several polling centers, so they went home without casting ballots.

"I'm disappointed. We're missing the chance to make a change," lawyer Raed Najm told The Associated Press after failing to find his name at four separate polling stations.

Jana Hybaskova, the European Union envoy to Iraq, described similar voter registration problems at polling sites in Baghdad's upscale Mansour district, a mixed Sunni-Shiite area.

Sunni lawmaker Mohammed al-Khaldi from the opposition Iraqiya bloc said he received complaints from voters in Baghdad and in Diyala province about missing names on voting rolls as well.

He also accused Shiite militiamen of burning ballot boxes in Diyala, which is home to both Sunni and Shiite Muslims.

Al-Shuraifi, the electoral official, confirmed that ballot boxes were destroyed in the province, but he blamed the act on angry voters who could not find their names on voting lists.

Voting took place at more than 5,300 polling centers for members of provincial councils who will serve in 12 of Iraq's 18 governorates.

Officials last month unexpectedly delayed voting in two largely Sunni provinces, citing security concerns. The provinces, Anbar and Ninevah, have witnessed four months of large anti-government protests, raising questions about the motives behind the delay.

The U.S. Embassy praised Iraqis for going to the polls in what it called a strong rejection of violent extremists. At the same time, it urged authorities in Baghdad to revisit the decision to delay the vote in the two Sunni provinces and to schedule voting there soon.

"Security concerns should not prevent all Iraqi citizens from expressing themselves democratically at the ballot box," the Embassy said in a statement.

Iraq's largely autonomous northern Kurdish region, which comprises three provinces, will hold its own local elections in September. No vote is scheduled in the ethnically disputed province of Kirkuk, which has not had a chance to elect local officials since 2005 because residents cannot agree on a power-sharing formula there.

As in the 2010 national elections, al-Maliki's Shiite-dominated State of Law coalition is vying against the Sunni-backed Iraqiya bloc. But Iraqiya is now fragmented with some prominent Sunni figures fielding their own slates of candidates.

State of Law also faces a challenge from Shiite rivals the Supreme Iraqi Islamic Council and followers of anti-American cleric Muqtada al-Sadr. A strong showing by them could undermine support for al-Maliki's bloc heading into next year's parliamentary elections.

Governorate councils choose provincial governors and have the right under Iraq's constitution to call for a referendum to organize themselves into a federal region ? a move that could give them considerable autonomy from the central government in Baghdad. They also have some say over regional security matters and the ability to negotiate local business deals and allocate government funds.

Some 13.8 million voters were eligible to participate in the provinces taking part in Saturday's vote.

___

Associated Press writers Qassim Abdul-Zahra, Sameer N. Yacoub and Sinan Salaheddin in Baghdad, and Nabil al-Jurani in Basra contributed reporting.

___

Follow Adam Schreck on Twitter at http://twitter.com/adamschreck

Source: http://news.yahoo.com/iraqis-polls-first-time-since-us-pullout-182855329.html

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Iraqis go to polls for first time since U.S. pullout

BAGHDAD (AP) ? Iraq carried out its first election since the U.S. military withdrawal without major bloodshed Saturday in a major test for Iraqi security forces as they face a reviving al-Qaida insurgency. But delayed elections in two provinces wracked by anti-government protests and complaints about missing names on voter rolls overshadowed the vote.

The results will be a key measure of support for the country's vying political coalitions and could boost the victors' chances heading into next year's parliamentary elections. Thousands of candidates from 50 electoral blocs were vying for 378 seats on provincial councils, which hold sway over public works projects and other decisions at the local level.

Officials ratcheted up security to thwart insurgent attempts to disrupt the vote. Nearly all cars were ordered off the roads in major cities, leaving streets eerily empty and giving children a chance to play soccer in the middle of highways.

Scattered violence ? mainly mortar shells and small bombs ? struck near polling places. But they resulted in no fatalities ? a departure from a wave of bloodshed earlier in the week. Six people were reported wounded Saturday.

As in past elections, voters dipped their fingers in purple ink after casting their ballots to prevent repeat voting.

Among them was Oday Mohammed, a businessman who brought his mother, wife and children along with him to vote for a candidate from Prime Minister Nouri al-Maliki's State of Law bloc. He said he believes both candidates and voters are growing more experienced with the democratic process following the 2003 ouster of dictator Saddam Hussein.

"Not all politicians are corrupt. There are some good people," he said at a polling center in the mainly Shiite district of Kazimiyah.

The vote comes at a time of rising tensions between Iraq's Sunni Arab minority and the Shiite majority that has dominated politics since the U.S.-led invasion a decade ago.

In a reflection of those sectarian strains, many voters said they were encouraged to participate by religious leaders.

"I don't have any hope that the situation will improve, but I had to take part because our clerics asked us to so we don't lose out like in in the past," said Anwar al-Obaidi, a 60-year old Sunni barber in Baghdad.

Muqdad al-Shuraifi, a member of the electoral commission, said after polls closed that a preliminary count showed 51 percent of eligible voters cast ballots. That is the same turnout as during the last provincial elections in 2009.

Full election results were not expected for several days.

Many Iraqis are frustrated with the lack of progress despite several earlier regional and national elections, which were protected with help from the U.S. Several said they saw no point in casting ballots.

"All the politicians and provincial officials, whether Sunni or Shiite, are nothing but thieves and liars," said Ali Farhan, a 35-year-old taxi driver in eastern Baghdad, in explaining his choice not to vote.

Militants stepped up attacks ahead of the vote. A wave of car bombings and other attacks Monday killed at least 55 people and wounded more than 200. Another bombing at a packed cafe late Thursday that left 32 dead. And at least 14 candidates were assassinated in recent weeks.

Several would-be voters in Baghdad's mainly Sunni neighborhood of Azamiyah could not find their names on voting rolls at several polling centers, so they went home without casting ballots.

"I'm disappointed. We're missing the chance to make a change," lawyer Raed Najm told The Associated Press after failing to find his name at four separate polling stations.

Jana Hybaskova, the European Union envoy to Iraq, described similar voter registration problems at polling sites in Baghdad's upscale Mansour district, a mixed Sunni-Shiite area.

Sunni lawmaker Mohammed al-Khaldi from the opposition Iraqiya bloc said he received complaints from voters in Baghdad and in Diyala province about missing names on voting rolls as well.

He also accused Shiite militiamen of burning ballot boxes in Diyala, which is home to both Sunni and Shiite Muslims.

Al-Shuraifi, the electoral official, confirmed that ballot boxes were destroyed in the province, but he blamed the act on angry voters who could not find their names on voting lists.

Voting took place at more than 5,300 polling centers for members of provincial councils who will serve in 12 of Iraq's 18 governorates.

Officials last month unexpectedly delayed voting in two largely Sunni provinces, citing security concerns. The provinces, Anbar and Ninevah, have witnessed four months of large anti-government protests, raising questions about the motives behind the delay.

The U.S. Embassy praised Iraqis for going to the polls in what it called a strong rejection of violent extremists. At the same time, it urged authorities in Baghdad to revisit the decision to delay the vote in the two Sunni provinces and to schedule voting there soon.

"Security concerns should not prevent all Iraqi citizens from expressing themselves democratically at the ballot box," the Embassy said in a statement.

Iraq's largely autonomous northern Kurdish region, which comprises three provinces, will hold its own local elections in September. No vote is scheduled in the ethnically disputed province of Kirkuk, which has not had a chance to elect local officials since 2005 because residents cannot agree on a power-sharing formula there.

As in the 2010 national elections, al-Maliki's Shiite-dominated State of Law coalition is vying against the Sunni-backed Iraqiya bloc. But Iraqiya is now fragmented with some prominent Sunni figures fielding their own slates of candidates.

State of Law also faces a challenge from Shiite rivals the Supreme Iraqi Islamic Council and followers of anti-American cleric Muqtada al-Sadr. A strong showing by them could undermine support for al-Maliki's bloc heading into next year's parliamentary elections.

Governorate councils choose provincial governors and have the right under Iraq's constitution to call for a referendum to organize themselves into a federal region ? a move that could give them considerable autonomy from the central government in Baghdad. They also have some say over regional security matters and the ability to negotiate local business deals and allocate government funds.

Some 13.8 million voters were eligible to participate in the provinces taking part in Saturday's vote.

___

Associated Press writers Qassim Abdul-Zahra, Sameer N. Yacoub and Sinan Salaheddin in Baghdad, and Nabil al-Jurani in Basra contributed reporting.

___

Follow Adam Schreck on Twitter at http://twitter.com/adamschreck

Source: http://news.yahoo.com/iraqis-polls-first-time-since-us-pullout-182855329.html

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Scott Porter Marries Kelsey Mayfield!

Source: http://www.thehollywoodgossip.com/2013/04/scott-porter-marries-kelsey-mayfield/

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My Songs - Your Forum Is Glued To A Site On Fire

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- Welcome to our new moderators: a_doubt, Automatic Writing, Chili_Pat and patches!

Source: http://www.yourforumisgluedtoasiteonfire.net/topic/5425-my-songs-thepoetslb/

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Dartmouth Discovery: Journals | Dartmouth Now

Dartmouth?s prolific scholars contribute to the creation of new knowledge and the advancement of their disciplines in many ways?one of which is publishing their discoveries and commentary in peer-reviewed journals.

From psychiatry to robotics, the work of Dartmouth researchers produced more than 60 articles in March 2013. See a full list of those publications below, and follow Dartmouth research on Twitter @dartdiscovery.

Publications in Peer-Reviewed Journals, March 2013

Antwi-Boampong, S., & Belbruno, J. J. (2013). Detection of formaldehyde vapor using conductive polymer films. Sensors and Actuators, B: Chemical, 182, 300-306. doi:10.1016/j.snb.2013.03.008

Baker, K. R. (2013). Computational results for the flowshop tardiness problem. Computers & Industrial Engineering, 64(3), 812-816. doi:10.1016/j.cie.2012.12.018

Banse, R., Imhoff, R., Steffens, M., Schramm, N., Roesch, A., Roberts, M., & Stangier, U. (2013). Partner-AMP and well-being: Evidence for an implicit secure base script? Personal Relationships, 20(1), 140-154. doi:10.1111/j.1475-6811.2012.01401.x

Bartels, S. J., Bruce, M. L., Unuetzer, J., & Blow, F. (2013). Developing the next generation of researchers in emerging fields: Case study of a multisite postdoctoral research training program. Academic Psychiatry, 37(2), 108-113.

Calude, C. S., Calude, E., & Queen, M. S. (2013). Inductive complexity of the P versus np problem. Parallel Processing Letters, 23(1), -1. doi:10.1142/S0129626413500072

Cerda, M., Bordelois, P. M., Galea, S., Norris, F., Tracy, M., & Koenen, K. C. (2013). The course of posttraumatic stress symptoms and functional impairment following a disaster: What is the lasting influence of acute versus ongoing traumatic events and stressors? Social Psychiatry and Psychiatric Epidemiology, 48(3), 385-395. doi:10.1007/s00127-012-0560-3

Chan, C. S., & Dover, J. S. (2013). Nd:YAG laser hair removal in Fitzpatrick skin types IV to VI. Journal of Drugs in Dermatology, 12(3), 366-367.

Cheng, C., Mathews, D. E., Schaller, G. E., & Kieber, J. J. (2013). Cytokinin-dependent specification of the functional megaspore in the arabidopsis female gametophyte. Plant Journal, 73(6), 929-940. doi:10.1111/tpj.12084

Cohen, L., Diether, K., & Malloy, C. (2013). Misvaluing innovation. Review of Financial Studies, 26(3), 635-666. doi:10.1093/rfs/hhs183

Crepet, W. L., Nixon, K. C., & Daghlian, C. P. (2013). Fossil ericales from the upper cretaceous of New Jersey. International Journal of Plant Sciences, 174(3), 572-584. doi:10.1086/668689

Currie, D. H., Herring, C. D., Guss, A. M., Olson, D. G., Hogsett, D. A., & Lynd, L. R. (2013). Functional heterologous expression of an engineered full length CipA from clostridium thermocellum in thermoanaerobacterium saccharolyticum. Biotechnology for Biofuels, 6, 32. doi:10.1186/1754-6834-6-32

Davis, J. M., Gandhi, R., & Kothari, V. H. (2013). Combinatorial algorithms for minimizing the weighted sum of completion times on a single machine. Operations Research Letters, 41(2), 121-125. doi:10.1016/j.orl.2012.12.001

Dijkstra, J. A., Buckman, K. L., Ward, D., Evans, D. W., Dionne, M., & Chen, C. Y. (2013). Experimental and natural warming elevates mercury concentrations in estuarine fish. Plos One, 8(3), e58401. doi:10.1371/journal.pone.0058401

Falardeau, J., Lobb, B. M., Golden, S., Maxfield, S. D., & Tanne, E. (2013). The use of acetazolamide during pregnancy in intracranial hypertension patients. Journal of Neuro-Ophthalmology, 33(1), 9-12. doi:10.1097/WNO.0b013e3182594001

Feiden, G. A., & Dotter, A. (2013). The interior structure constants as an age diagnostic for low-mass, pre-main-sequence detached eclipsing binary stars. Astrophysical Journal, 765(2), 86. doi:10.1088/0004-637X/765/2/86

Feiler, D. C., Tong, J. D., & Larrick, R. P. (2013). Biased judgment in censored environments. Management Science, 59(3), 573-591. doi:10.1287/mnsc.1120.1612

Freeman, J. B., & Dale, R. (2013). Assessing bimodality to detect the presence of a dual cognitive process. Behavior Research Methods, 45(1), 83-97. doi:10.3758/s13428-012-0225-x

Freeman, J. B., Ma, Y., Han, S., & Ambady, N. (2013). Influences of culture and visual context on real-time social categorization. Journal of Experimental Social Psychology, 49(2), 206-210. doi:10.1016/j.jesp.2012.10.015

Fuller, K. K., Ringelberg, C. S., Loros, J. J., & Dunlap, J. C. (2013). The fungal pathogen aspergillus fumigatus regulates growth, metabolism, and stress resistance in response to light. Mbio, 4(2) doi:10.1128/mBio.00142-13

Gerst, M. D., Howarth, R. B., & Borsuk, M. E. (2013). The interplay between risk attitudes and low probability, high cost outcomes in climate policy analysis. Environmental Modelling & Software, 41, 176-184. doi:10.1016/j.envsoft.2012.12.004

Glaser, A. K., Voigt, W. H. A., Davis, S. C., Zhang, R., Gladstone, D. J., & Pogue, B. W. (2013). Three-dimensional Cerenkov tomography of energy deposition from ionizing radiation beams. Optics Letters, 38(5), 634-636.

Gribble, G. W. (2013). Food chemistry and chemophobia. Food Security, 5(2), 177-187. doi:10.1007/s12571-013-0251-2

Groszek, M. J. (2013). Ramsey properties of countably infinite partial orderings. Electronic Journal of Combinatorics, 20(1), P50.

Gulbas, L. E. (2013). Embodying racism: Race, rhinoplasty, and self-esteem in Venezuela. Qualitative Health Research, 23(3), 326-335. doi:10.1177/1049732312468335

Hartford, A. C., Paravati, A. J., Spire, W. J., Li, Z., Jarvis, L. A., Fadul, C. E., Rhodes, C.H., Erkmen, K., Gladstone, D.J., Roberts, D.W., . . . & Simmons, N. E. (2013). Postoperative stereotactic radiosurgery without whole-brain radiation therapy for brain metastases: Potential role of preoperative tumor size. International Journal of Radiation Oncology Biology Physics, 85(3), 650-655. doi:10.1016/j.ijrobp.2012.05.027

Herron, M. C. (2013). Blacks, Hispanics, and Whites: A study of race-based residual vote rates in Chicago. American Politics Research, 41(2), 203-243. doi:http://dx.doi.org/10.1177/1532673X12453759

Hunger, P. M., Donius, A. E., & Wegst, U. G. K. (2013). Platelets self-assemble into porous nacre during freeze casting. Journal of the Mechanical Behavior of Biomedical Materials, 19, 87-93. doi:10.1016/j.jmbbm.2012.10.013

Hurley, J. M. 1., & Dunlap, J. C. (2013). Cell biology: A fable of too much too fast. Nature, 495(7439), 57-58. doi:10.1038/nature11952

Jordan, J., Brown, M. E., Trevi?o, L. K., & Finkelstein, S. (2013). Someone to look up to: Executive?follower ethical reasoning and perceptions of ethical leadership. Journal of Management, 39(3), 660-683. doi:http://dx.doi.org/10.1177/0149206311398136

Kasprak, A., Magilligan, F. J., Nislow, K. H., Renshaw, C. E., Snyder, N. P., & Dade, W. B. (2013). Differentiating the relative importance of land cover change and geomorphic processes on fine sediment sequestration in a logged watershed. Geomorphology, 185, 67-77. doi:10.1016/j.geomorph.2012.12.005

Keeney, B. J., Fulton-Kehoe, D., Wickizer, T. M., Turner, J. A., Chan, K. C. G., & Franklin, G. M. (2013). Clinically significant weight gain 1 year after occupational back injury. Journal of Occupational and Environmental Medicine, 55(3), 318-324. doi:10.1097/JOM.0b013e31827943c6

Laflamme, M., Darroch, S. A. F., Tweedt, S. M., Peterson, K. J., & Erwin, D. H. (2013). The end of the ediacara biota: Extinction, biotic replacement, or Cheshire cat? Gondwana Research, 23(2), 558-573. doi:10.1016/j.gr.2012.11.004

Lamb, G. C., Smith, M. A., Weeks, W. B., & Queram, C. (2013). Publicly reported quality-of-care measures influenced Wisconsin physician groups to improve performance. Health Affairs, 32(3), 536-543. doi:10.1377/hlthaff.2012.1275

Lamppa, J. W., Tanyos, S. A., & Griswold, K. E. (2013). Engineering escherichia coli for soluble expression and single step purification of active human lysozyme. Journal of Biotechnology, 164(1), 1-8. doi:10.1016/j.jbiotec.2012.11.007

Laughney, A. M., Krishnaswamy, V., Rice, T. B., Cuccia, D. J., Barth, R. J., Tromberg, B. J., Paulsen, K.D., Pogue, B.W., & Wells, W. A. (2013). System analysis of spatial frequency domain imaging for quantitative mapping of surgically resected breast tissues. Journal of Biomedical Optics, 18(3), 36012-36012. doi:10.1117/1.JBO.18.3.036012

Lerner, F. A. (2013). RE: PILOTS database [letter]. Military Medicine, 178(3), vii.

Lever, J. H., Delaney, A. J., Ray, L. E., Trautmann, E., Barna, L. A., & Burzynski, A. M. (2013). Autonomous GPR surveys using the polar rover Yeti. Journal of Field Robotics, 30(2), 194-215. doi:10.1002/rob.21445

Lewis, V. A., MacGregor, C. A., & Putnam, R. D. (2013). Religion, networks, and neighborliness: The impact of religious social networks on civic engagement. Social Science Research, 42(2), 331-346. doi:10.1016/j.ssresearch.2012.09.011

Lewis, V. A., McClurg, A. B., Smith, J., Fisher, E. S., & Bynum, J. P. W. (2013). Attributing patients to accountable care organizations: Performance year approach aligns stakeholders? interests. Health Affairs, 32(3), 587-95.

Lowell, T. V., Hall, B. L., Kelly, M. A., Bennike, O., Lusas, A. R., Honsaker, W., Levy, L.B., . . . & Denton, G. H. (2013). Late Holocene expansion of istorvet ice cap, Liverpool land, east Greenland. Quaternary Science Reviews, 63, 128-140. doi:10.1016/j.quascirev.2012.11.012

Melin, A. D., Matsushita, Y., Moritz, G. L., Dominy, N. J., & Kawamura, S. (2013). Inferred L/M cone opsin polymorphism of ancestral tarsiers sheds dim light on the origin of anthropoid primates. Proceedings.Biological Sciences / the Royal Society, 280(1759), 20130189-20130189. doi:10.1098/rspb.2013.0189

Merritt, M. A., Cramer, D. W., Vitonis, A. F., Titus, L. J., & Terry, K. L. (2013). Dairy foods and nutrients in relation to risk of ovarian cancer and major histological subtypes. International Journal of Cancer, 132(5), 1114-1124. doi:10.1002/ijc.27701

Mollett, S., & Faria, C. (2013). Messing with gender in feminist political ecology. Geoforum, 45, 116-125. doi:10.1016/j.geoforum.2012.10.009

Nair, A., Thomas, A. C., & Borsuk, M. E. (2013). Interannual variability in the timing of New England shellfish toxicity and relationships to environmental forcing. The Science of the Total Environment, 447, 255-66. doi:10.1016/j.scitotenv.2013.01.023

Najjar, S., Pearlman, D., Devinsky, O., Najjar, A., Nadkarni, S., Butler, T., & Zagzag, D. (2013). Neuropsychiatric autoimmune encephalitis without VGKC-complex, NMDAR, and GAD autoantibodies: Case report and literature review. Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology, 26(1), 36-49. doi:10.1097/WNN.0b013e31828b6531

Oulvey, E., Carpenter-Song, E. A., & Swanson, S. J. (2013). Principles for enhancing the role of state vocational rehabilitation in IPS-supported employment. Psychiatric Rehabilitation Journal., 36(1), 4-6. doi:http://dx.doi.org/10.1037/h0094740

Pande, M., Thompson, P. A., Do, K., Sahin, A. A., Amos, C. I., Frazier, M. L., . . . & Brewster, A. M. (2013). Genetic variants in the vitamin D pathway and breast cancer disease-free survival. Carcinogenesis, 34(3), 587-594. doi:10.1093/carcin/bgs369

Periyakoil, V. S., Stevens, M., & Kraemer, H. (2013). Multicultural long-term care nurses? perceptions of factors influencing patient dignity at the end of life. Journal of the American Geriatrics Society, 61(3), 440-446. doi:10.1111/jgs.12145

Powell, S. G. (2013). Pricing early-exercise options using genetic optimization. Journal of Derivatives, 20(3), 43-59

Ran, C., Liu, H., Hitoshi, Y., & Israel, M. A. (2013). Proliferation-independent control of tumor glycolysis by PDGFR-mediated AKT activation. Cancer Research, 73(6), 1831-1843. doi:10.1158/0008-5472.CAN-12-2460

Robinson, J. M., Sperling, E. A., Bergum, B., Adamski, M., Nichols, S. A., Adamska, M., & Peterson, K. J. (2013). The identification of MicroRNAs in calcisponges: Independent evolution of MicroRNAs in basal metazoans. Journal of Experimental Zoology Part B-Molecular and Developmental Evolution, 320B(2), 84-93. doi:10.1002/jez.b.22485

Roskies, A. L., Schweitzer, N. J., & Saks, M. J. (2013). Neuroimages in court: Less biasing than feared. Trends in Cognitive Sciences, 17(3), 99-101. doi:10.1016/j.tics.2013.01.008

Schaeffer, R. N., Manson, J. S., & Irwin, R. E. (2013). Effects of abiotic factors and species interactions on estimates of male plant function: A meta-analysis. Ecology Letters, 16(3), 399-408. doi:10.1111/ele.12044

Schulson, E. M., & Fortt, A. L. (2013). Static strengthening of frictional surfaces of ice. Acta Materialia, 61(5), 1616-1623. doi:10.1016/j.actamat.2012.11.038

Sculli, G. L., Fore, A. M., West, P., Neily, J., Mills, P. D., & Paull, D. E. (2013). Nursing crew resource management: A follow-up report from the veterans health administration. Journal of Nursing Administration, 43(3), 122-126. doi:10.1097/NNA.0b013e318283dafa

Shakeel, S. N., Wang, X., Binder, B. M., & Schaller, G. E. (2013). Mechanisms of signal transduction by ethylene: Overlapping and non-overlapping signalling roles in a receptor family. AoB Plants, 5, plt010-plt010. doi:10.1093/aobpla/plt010

St Lawrence, K., Verdecchia, K., Elliott, J., Tichauer, K., Diop, M., Hoffman, L., & Lee, T. (2013) Kinetic model optimization for characterizing tumour physiology by dynamic contrast-enhanced near-infrared spectroscopy. Physics in Medicine and Biology, 58(5), 1591-1604. doi:10.1088/0031-9155/58/5/1591

Stauth, J. T., Seeman, M. D., & Kesarwani, K. (2013). Resonant switched-capacitor converters for sub-module distributed photovoltaic power management. Ieee Transactions on Power Electronics, 28(3), 1189-1198. doi:10.1109/TPEL.2012.2206056

Stock, M. L., Gibbons, F. X., Gerrard, M., Houlihan, A. E., Weng, C., Lorenz, F. O., & Simons, R. L. (2013). Racial identification, racial composition, and substance use vulnerability among African American adolescents and young adults. Health Psychology, 32(3), 237-247. doi:10.1037/a0030149

Suh, S. (2013). Stories to be told: Korean doctors between hwa-byung (fire-illness) and depression, 1970-2011. Culture Medicine and Psychiatry, 37(1), 81-104. doi:10.1007/s11013-012-9291-x

Wallace, D. I., & Guo, X. (2013). Properties of tumor spheroid growth exhibited by simple mathematical models. Frontiers in Oncology, 3, 51-51. doi:10.3389/fonc.2013.00051

Wang, H., Chen, Y., Xun, S., Lai, D., Fan, Y., & Li, Z. (2013). Changes in daily climate extremes in the arid area of northwestern China. Theoretical and Applied Climatology, 112(1-2), 15-28. doi:10.1007/s00704-012-0698-7

Wang, X., Li, H., Camacho-Aguilera, R., Cai, Y., Kimerling, L. C., Michel, J., & Liu, J. (2013). Infrared absorption of n-type tensile-strained ge-on-si. Optics Letters, 38(5), 652-654.

Whedon, J. M., Rugo, N. A., & Lux, K. (2013). Challenges of withdrawal from chronic antidepressant medication: A healing odyssey. Explore-the Journal of Science and Healing, 9(2), 108-111. doi:10.1016/j.explore.2012.12.003

Wittink, M. N., Morales, K. H., Cary, M., Gallo, J. J., & Bartels, S. J. (2013). Towards personalizing treatment for depression. Patient-Patient Centered Outcomes Research, 6(1), 35-43. doi:10.1007/s40271-013-0003-6

Wu, C., Shete, S., Jo, E., Xu, Y., Lu, E. Y., Chen, W. V., & Amos, C. I. (2013). Whole-genome detection of disease-associated deletions or excess homozygosity in a case-control study of rheumatoid arthritis. Human Molecular Genetics, 22(6), 1249-1261. doi:10.1093/hmg/dds512

Wu, X., & Baker, I. (2013). Dislocations in nanostructured two-phase Fe30Ni20Mn20Al30. Microscopy Research and Technique, 76(3), 263-267. doi:10.1002/jemt.22162

Yatawara, A. K., Hodoscek, M., & Mierke, D. F. (2013). Ligand binding site identification by higher dimension molecular dynamics. Journal of Chemical Information and Modeling, 53(3), 674-680. doi:10.1021/ci300561b

Zhaxybayeva, O., Stepanauskas, R., Mohan, N. R., & Papke, R. T. (2013). Cell sorting analysis of geographically separated hypersaline environments. Extremophiles, 17(2), 265-275. doi:10.1007/s00792-013-0514-z

ABOUT THIS LIST

This list of publications was compiled with the counsel of the Dartmouth College Library using the following academic search services and databases:

• Ebscohost
• Engineering Village
• ProQuest
• Web of Knowledge

We strive to make this information as accurate and comprehensive as possible, and welcome requests for corrections or additions at dartmouth.now@dartmouth.edu.

Source: http://now.dartmouth.edu/2013/04/dartmouth-discovery-journals-8/

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Impromptu Mobile Nations video podcast. Sorta.

I just arrived in New York City to start prep work on [Redacted] -- watch the video above for a gigantic tease -- so I video bombed Kevin Michaluk's CrackBerry podcast, along with Alex Dobie of Android Central.

Check it out.

Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/9zOB4W1BlmQ/story01.htm

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World's Oldest Spacewalker: Russian Cosmonaut Makes Space History at 59

Russian cosmonaut Pavel Vinogradov made spaceflight history high above Earth on Friday (April 19) when, at age 59, ?he became the oldest person ever to venture outside a spacecraft during a spacewalk that was only marred by the last-minute loss of an experiment.

Vinogradov, a veteran cosmonaut, took his seventh cosmic excursion in 16 years during Friday's spacewalk. He donned a bulky spacesuit and left the confines of the?International Space Station?just after 10 a.m. EDT (1400 GMT) to upgrade the orbiting lab with new experiments.?

Vinogradov paired up with 41-year-old fellow cosmonaut Roman Romanenko, a first-time spacewalker but second-generation cosmonaut. Romanenko's father, former cosmonaut Yuri Romanenko, logged more than 10 spacewalking hours in his career.

The spacewalkers were at times lighthearted during the more-than-six-hour job.

"Nobody took a photo of me," Romanenko jokingly protested aftering they used a camera to take pictures outside the lab. "How can it be like that? Please take a photo of me, Pavel."

In the last task of the spacewalk, Vinogradov was attempting to retrieve a panel from the Russian materials exposure experiment called Vinoslivost, but the panel flew out of his grasp before he had a chance to tether it. The cosmonauts were unable to recover the piece.

Flight controllers do not believe the 6.5-pound (3-kg) panel, which measured 18 inches by 12 inches (45 cm by 30 cm), hit any part of the space station. NASA announcers noted that there is another Vinoslivost panel still attached to the space station that will be retrieved in a future spacewalk, so all is not lost from the experiment.

Vinogradov and Romanenko's primary objective was to install a new Russian experiment called Obstanovka, which will measure charged particles interact with a variety of materials kept outside of the space station. Obstanovka could offer scientists new insights about how?space weather?affects the ionosphere, an active region of the Earth's atmosphere, NASA officials explained in a spacewalk description.

The pair also successfully retrieved a Biorisk canister, an experiment that measures the effects of bacteria and fungus on spacecraft materials, and prepared the outpost for the arrival of a robotic cargo ship later this year.

The spacewalkers are two members of the six-man Expedition 35 crew currently living aboard the International Space Station. The others are Canadian astronaut Chris Hadfield, Russian cosmonaut Alexander Misurkin, and NASA astronauts Thomas Marshburn and Chris Cassidy.

This was the 167th spacewalk dedicated to the construction and upkeep of the International Space Station, which was built by five different space agencies representing 15 countries. Construction of the $100 billion space station began in 1998, and it has been permanently staffed with rotating crews since 2000. It is roughly the size of a five-bedroom house with a wingspan the size of a football field.

Follow us?@Spacedotcom,?Facebook?and?Google+. Originally published on?SPACE.com.

Copyright 2013 SPACE.com, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://news.yahoo.com/worlds-oldest-spacewalker-russian-cosmonaut-makes-space-history-201516346.html

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Increased brain activity predicts future onset of substance use

Apr. 17, 2013 ? Do people get caught in the cycle of overeating and drug addiction because their brain reward centers are over-active, causing them to experience greater cravings for food or drugs?

In a unique prospective study Oregon Research Institute (ORI) senior scientist Eric Stice, Ph.D., and colleagues tested this theory, called the reward surfeit model. The results indicated that elevated responsivity of reward regions in the brain increased the risk for future substance use, which has never been tested before prospectively with humans. Paradoxically, results also provide evidence that even a limited history of substance use was related to less responsivity in the reward circuitry, as has been suggested by experiments with animals.

The research appears in the May 1, 2013 issue of Biological Psychiatry.

In a novel study using functional Magnetic Resonance Imaging (fMRI) Stice's team tested whether individual differences in reward region responsivity predicted overweight/obesity onset among initially healthy weight adolescents and substance use onset among initially abstinent adolescents. The neural response to food and monetary reward was measured in 162 adolescents. Body fat and substance use were assessed at the time of the fMRI and again one year later.

"The findings are important because this is the first test of whether atypical responsivity of reward circuitry increases risk for substance use," says Dr. Stice. "Although numerous researchers have suggested that reduced responsivity is a vulnerability factor for substance use, this theory was based entirely on cross-sectional studies comparing substance abusing individuals to healthy controls; no studies have tested this thesis with prospective data."

Investigators examined the extent to which reward circuitry (e.g., the striatum) was activated in response to receipt and anticipated receipt of money. Monetary reward is a general reinforcer and has been used frequently to assess reward sensitivity. The team also used another paradigm to assess brain activation in response to the individual's consumption and anticipated consumption of chocolate milkshake. Results showed that greater activation in the striatum during monetary reward receipt at baseline predicted future substance use onset over a 1-year follow-up.

Noteworthy was that adolescents who had already begun using substances showed less striatal response to monetary reward. This finding provides the first evidence that even a relatively short period of moderate substance use might reduce reward region responsivity to a general reinforcer.

"The implications are that the more individuals use psychoactive substances, the less responsive they will be to rewarding experiences, meaning that they may derive less reinforcement from other pursuits, such as interpersonal relationships, hobbies, and school work. This may contribute to the escalating spiral of drug use that characterizes substance use disorders," commented Stice.

Although the investigators had expected parallel neural predictors of future onset of overweight during exposure to receipt and anticipated receipt of a palatable food, no significant effects emerged. It is possible that these effects are weaker and that a longer follow-up period will be necessary to better differentiate who will gain weight and who will remain at a healthy weight.

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The above story is reprinted from materials provided by Oregon Research Institute, via EurekAlert!, a service of AAAS.

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Journal Reference:

1. Eric Stice, Sonja Yokum, Kyle S. Burger. Elevated Reward Region Responsivity Predicts Future Substance Use Onset But Not Overweight/Obesity Onset. Biological Psychiatry, 2013; 73 (9): 869 DOI: 10.1016/j.biopsych.2012.11.019

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Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/gnD24aukvZ8/130418100152.htm

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Wall Street bounces back on data, earnings

Apr 15 (Reuters) - Leading money winners on the 2013 PGATour on Monday (U.S. unless stated): 1. Tiger Woods $4,139,600 2. Brandt Snedeker $3,137,920 3. Matt Kuchar $2,442,389 4. Adam Scott (Australia) $2,100,469 5. Steve Stricker $1,935,340 6. Phil Mickelson $1,764,680 7. Dustin Johnson $1,748,907 8. Jason Day $1,659,565 9. Hunter Mahan $1,553,965 10. Keegan Bradley $1,430,347 11. Charles Howell III $1,393,806 12. John Merrick $1,375,757 13. Russell Henley $1,331,434 14. Michael Thompson $1,310,709 15. Kevin Streelman $1,310,343 16. Bill Haas $1,271,553 17. Billy Horschel $1,254,224 18. ...

Source: http://news.yahoo.com/stock-futures-signal-higher-wall-street-open-083126953--finance.html

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Acute stress primes brain for better cognitive and mental performance

Apr. 16, 2013 ? Overworked and stressed out? Look on the bright side. Some stress is good for you.

"You always think about stress as a really bad thing, but it's not," said Daniela Kaufer, associate professor of integrative biology at the University of California, Berkeley. "Some amounts of stress are good to push you just to the level of optimal alertness, behavioral and cognitive performance."

New research by Kaufer and UC Berkeley post-doctoral fellow Elizabeth Kirby has uncovered exactly how acute stress -- short-lived, not chronic -- primes the brain for improved performance.

In studies on rats, they found that significant, but brief stressful events caused stem cells in their brains to proliferate into new nerve cells that, when mature two weeks later, improved the rats' mental performance.

"I think intermittent stressful events are probably what keeps the brain more alert, and you perform better when you are alert," she said.

Kaufer, Kirby and their colleagues in UC Berkeley's Helen Wills Neuroscience Institute describe their results in a paper published April 16 in the new open access online journal eLife.

The UC Berkeley researchers' findings, "in general, reinforce the notion that stress hormones help an animal adapt -- after all, remembering the place where something stressful happened is beneficial to deal with future situations in the same place," said Bruce McEwen, head of the Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology at The Rockefeller University, who was not involved in the study.

Kaufer is especially interested in how both acute and chronic stress affect memory, and since the brain's hippocampus is critical to memory, she and her colleagues focused on the effects of stress on neural stem cells in the hippocampus of the adult rat brain. Neural stem cells are a sort of generic or progenitor brain cell that, depending on chemical triggers, can mature into neurons, astrocytes or other cells in the brain. The dentate gyrus of the hippocampus is one of only two areas in the brain that generate new brain cells in adults, and is highly sensitive to glucocorticoid stress hormones, Kaufer said.

Much research has demonstrated that chronic stress elevates levels of glucocorticoid stress hormones, which suppresses the production of new neurons in the hippocampus, impairing memory. This is in addition to the effect that chronically elevated levels of stress hormones have on the entire body, such as increasing the risk of chronic obesity, heart disease and depression.

Less is known about the effects of acute stress, Kaufer said, and studies have been conflicting.

To clear up the confusion, Kirby subjected rats to what, to them, is acute but short-lived stress -- immobilization in their cages for a few hours. This led to stress hormone (corticosterone) levels as high as those from chronic stress, though for only a few hours. The stress doubled the proliferation of new brain cells in the hippocampus, specifically in the dorsal dentate gyrus.

Kirby discovered that the stressed rats performed better on a memory test two weeks after the stressful event, but not two days after the event. Using special cell labeling techniques, the researchers established that the new nerve cells triggered by the acute stress were the same ones involved in learning new tasks two weeks later.

"In terms of survival, the nerve cell proliferation doesn't help you immediately after the stress, because it takes time for the cells to become mature, functioning neurons," Kaufer said. "But in the natural environment, where acute stress happens on a regular basis, it will keep the animal more alert, more attuned to the environment and to what actually is a threat or not a threat."

They also found that nerve cell proliferation after acute stress was triggered by the release of a protein, fibroblast growth factor 2 (FGF2), by astrocytes -- brain cells formerly thought of as support cells, but that now appear to play a more critical role in regulating neurons.

"The FGF2 involvement is interesting, because FGF2 deficiency is associated with depressive-like behaviors in animals and is linked to depression in humans," McEwen said.

Kaufer noted that exposure to acute, intense stress can sometimes be harmful, leading, for example, to post-traumatic stress disorder. Further research could help to identify the factors that determine whether a response to stress is good or bad.

"I think the ultimate message is an optimistic one," she concluded. "Stress can be something that makes you better, but it is a question of how much, how long and how you interpret or perceive it."

The eLife paper was coauthored by UC Berkeley colleagues Sandra E Muroy, Wayne G. Sun and David Covarrubias of the Department of Molecular and Cell Biology; Megan J. Leong of the Helen Wills Neuroscience Institute; and Laurel A. Barchas of the Department of Integrative Biology. Kirby is now a post-doctoral fellow at Stanford University.

Kaufer's research was funded by a BRAINS (Biobehavioral Research Awards for Innovative New Scientists) award from the National Institute of Mental Health of the National Institutes of Health (R01 MH087495) and the National Alliance for Research on Schizophrenia and Depression. Kirby was supported by fellowships from the California Institute for Regenerative Medicine and the U.S. Department of Defense.

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The above story is reprinted from materials provided by University of California - Berkeley.

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Journal Reference:

1. Elizabeth D Kirby, Sandra E Muroy, Wayne G Sun, David Covarrubias, Megan J Leong, Laurel A Barchas, Daniela Kaufer. Acute stress enhances adult rat hippocampal neurogenesis and activation of newborn neurons via secreted astrocytic FGF2. eLife, April 16, 2013

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/99sVXZ3MXWo/130416204546.htm

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